Hi kamion
I prefer the focus to be on the eyes as in my opinion that's the most interesting bit, round the head and mouth.
Getting depth of field in macro stuff is difficult. You're working at close distances and depth of field is measured in millimetres. You need to stop the lens down to a minimum of F10 to get a workable depth of field and that introduces the problem of getting enough light into the camera to get a decent shutter speed. To get round that people generally use a separate flash unit.
Unfortunately with the set up I have it tends to mean you're too close to really get good light coverage so I can't get enough light into the picture to go for the really small apertures eg F16 and smaller. I need a lens like CT's or an off camera bracket