Need a bit of advice please......
Looking to purchase my next lens, I've done a fair bit of reading already but wanted to know if anyone had experience of either/both of the above lenses. On reading Fred Mir'da most reviews talk as thought the F2.8 is coming back with the sharper picture

not sure if these are just mostly low light shot or not.
The F2.8 does have the benefit when used with an extender as I understand I'd lose a couple of stops anyway. (Would possible pair up with a 2X ext'der)
Question then, is the F2.8 worth the extra £300 over and above the F4.
Cheers in advance